Gray Matter Deficits and Altered Resting-State Connectivity in the Superior Temporal Gyrus Among Individuals with Problematic Hypersexual Behavior

AUTHOR(S)

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PUBLISHED

2018 in Brain Research, Vol, 1684, 30-39

KEY FINDINGS
  • Compared to healthy subjects, individuals with hypersexual behavior had significant reductions in gray matter volume in the left superior temporal gyrus (STG) and right middle temporal gyrus.
ABSTRACT
Neuroimaging studies on the characteristics of hypersexual disorder have been accumulating, yet alternations in brain structures and functional connectivity in individuals with problematic hypersexual behavior (PHB) has only recently been studied. This study aimed to investigate gray matter deficits and resting-state abnormalities in individuals with PHB using voxel-based morphometry and resting-state connectivity analysis. Seventeen individuals with PHB and 19 age-matched healthy controls participated in this study. Gray... READ FULL ABSTRACT
EXCERPTS
  • "Compared to healthy subjects, individuals with PHB had signif-icantly decreased functional connectivity between the STG and thecaudate nucleus. A negative correlation was also observed betweenthe severity of PHB and functional connectivity between theseareas. Anatomically, the STG has direct connections with the cau-date nucleus (Yeterian and Pandya, 1998). The caudate nucleus isthe main subregion of the striatum, and is important for reward-based behavioral learning, intricately associated with pleasureand motivation, and related to the maintenance of addictive behaviors."
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